Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
BioRegion Real Estate
Millipore Anderson Facility, University of Massachusetts-Lowell Emerging Technology & Innovation Center, Boehringer Ingelheim Chemicals Petersburg, Va., Plant Expansion, Hamner Institutes for Health Sciences, LabCorp Biorepository, North Carolina Research Campus, Rowan-Cabarrus Community College, Economic Development Council of Tallahassee/Leon County, and others
New to GenomeWeb? Register quickly here for free access.