By modifying methods and analytical approaches, a team of researchers was able to sequence 26 marine microbial genomes and two marine metagenomes while on a research vessel in the Pacific Ocean. They brought an Ion Torrent PGM platform with them on the boat and were able to generate some 1.5 billion bases of high-quality sequence data from three Pseudoalteromonas, one Ruegeria, two Serratia, and 20 Vibrio isolates. They said their real-time analyses uncovered unique metabolic processes that may help bacteria survive in the region.
Illumina has partnered with AstraZeneca, Janssen Biotech, and Sanofi to develop a universal next-generation sequencing-based oncology test system for multi-analyte companion diagnostics. The new system will run assays that detect several variants in parallel and be used as part of the pharma partners' clinical trials of targeted cancer therapies. Illumina plans to develop, commercialize, and gain regulatory approval for multi-gene panels for therapy selection, as well as work to define regulatory frameworks for these types of tests.
The National Institute of General Medical Sciences will provide up to $2 million per year to renew funding for each of the National Centers for Systems Biology, pending approval of renewal applications. NIGMS currently funds 12 systems biology centers at institutions across the US that use a wide range of molecular, cellular, biochemical, behavioral, and other approaches to study complex biological phenomena. The systems biology centers program is currently under evaluation, NIGMS said, so it is not currently offering awards to fund new centers.
This online seminar will provide an overview of new tools for screening stem cells — in particular, the use of RNA detection probes to detect pluripotency gene expression in live embryonic and induced pluripotent stem cells by fluorescence microscopy without the need for manipulation of the cells.