Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Qiagen Gains New Array Resources in SABiosciences Deal
While Qiagen is primarily interested in SABiosciences' PCR Arrays and bioinformatics tools, the company also offers a number of microarray resources, including its own line of focused gene-expression arrays, a menu of reagent kits, data-analysis software, and core services on the Agilent Technologies and Illumina platforms.
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