Regulation and Function of miR-218 in Gastric Cancer Metastasis
Tie, Pan et al., PLoS Genetics
Researchers describe a negative feedback system between Robo1, a Slit receptor, and miR-218, wherein “decreased miR-218 levels eliminate Robo1 repression, which activates the Slit-Robo1 pathway through the interaction between Robo1 and Slit2, thus triggering tumor metastasis.” The authors suggest that the restoration of miR-218 supresses Robo1 espression and inhibits tumor cell invasion.
PlexPress Closes $2.75M Seed Funding Round, Plans to Launch TRAC Platform in Fall
PlexPress' transcription analysis with affinity capture platform was developed at Finland's VTT Technical Research Center to provide high-content gene-expression analysis of between two and 150 genes in up to several thousand samples.
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