Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Norwegian Startup Genetic Analysis to Offer Array-Based Microbiota Screening
According to CEO Morten Isaksen, a number of diseases are thought to be linked to an imbalance in the microbial profile of the gut, including inflammatory bowel disease, necrotizing enterocolitis, allergies, and autism.
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