PTB Proteins Induce RNA Looping
Lamichhane, Daubner et al., PNAS
Researchers in the US and Switzerland report that polypyrimidine tract-binding proteins induce RNA looping ― a finding they deduced using FRET, NMR spectroscopy, and in vivo splicing data. They show that two PTB RNA recognition motifs can bind two distant pyrimidine tracts, bringing their 5' and 3' ends in close proximity, thus inducing loop formation.
Genome-Wide Screen Turns Up Primate-Specific Genes
A team of researchers from the US and Singapore used comparative genomics to find genes that are present in the genomes of primates but absent from those of non-primates.
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