Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Court Constructs Claims in Illumina vs. Affymetrix IP Suit; Trial Date Moved to 2011
An ongoing IP dispute between array vendors Illumina and Affymetrix inched closer to resolution last week, as a US District Court ruled on the meanings of patent claims central to the case.
New to GenomeWeb? Register quickly here.