Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Casework Genetics Chooses Illumina Chips for Forensic Services
CEO Kevin McElfresh said Casework hopes to commercialize the technique, which uses the Illumina HumanOmni1-Quad BeadChip, by year end in order to upgrade its own offering and gain an advantage over rivals that use older technology.
New to GenomeWeb? Register quickly here.