Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Agilent Tech Bets New Array-Analysis Software Will Woo Systems Biologists
GeneSpring GX 10 users can now analyze data from gene-expression, microRNA-expression, alternative-splicing, and RT-PCR experiments. The upgrade is part of an industry-wide trend of enabling more customers to answer biological questions using multiple applications.
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