PTB Proteins Induce RNA Looping
Lamichhane, Daubner et al., PNAS
Researchers in the US and Switzerland report that polypyrimidine tract-binding proteins induce RNA looping ― a finding they deduced using FRET, NMR spectroscopy, and in vivo splicing data. They show that two PTB RNA recognition motifs can bind two distant pyrimidine tracts, bringing their 5' and 3' ends in close proximity, thus inducing loop formation.
Agilent to Debut Automated Liquid-Handling Workflow in Fall, High-Density Expression Chips in 2010
Agilent will launch an automated liquid-handling workflow by early October, and will add million-feature arrays in its high-density G3 format for expression profiling and location analysis studies within the next six to nine months.
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