Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Analyst Sees Stimulus Countering Funding Weakness Late in '09
The $10.4 million in additional NIH funding is expected to counteract continuing weakness from other sources of funding for life sciences research. In addition, researchers' spending plans seem to favor diversified firms with significant consumables revenue and diagnostics firms, according to a report.
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